ClickBank - best all in one (trust me)
PayDotCom - you can purchase with a CC it's not just a paypal ordering system, however you have to rely on each vendor paying you on time, PDC does not pay you or act as an intermediary.
Click2sell - as above
Plimus - ok
ejunkie - ok
Still nothing out there compares to CB for all-in-one solutions for aff's/pub's or those that do both. I would think twice before going elsewhere personally, you won't find the product lines, the affiliate support, or the tracking to be perfect ANYWHERE. I've gone through many networks on both the digital/info product side and the CPA side, and will confidently say that from a vendors standpoint, it will take a LOT for me to leave CB.